BOTOX® Cosmetic (onabotulinumtoxinA) targets one of the underlying causes of frown lines and crow’s feet—the repeated muscle contractions from frowning and squinting over the years. BOTOX® Cosmetic temporarily reduces this muscle activity so you’ll begin to notice a visible smoothing of these lines. For temporary improvement of moderate to severe crow’s feet, your doctor will inject BOTOX® Cosmetic into the muscle surrounding the sides of your eyes—called the orbicularis oculi muscles. For temporary improvement of moderate to severe frown lines, your doctor will inject BOTOX® Cosmetic into 2 muscles—the corrugator and procerus muscles.